HitPredict

Interactor 1: VTA1 (Q9NP79)
Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1)
Gene: VTA1

Interactor 2: CHMP5 (Q9NZZ3)
Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2) (Vacuolar protein sorting-associated protein 60) (Vps60) (hVps60)
Gene: CHMP5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.927

The method score is based on:

Property Details
Experiments 21543490, 28514442, 33961781, 17261583, 16730941
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Snf7~Vta1
Common GO terms GO:0005771 - multivesicular body
GO:0005829 - cytosol
GO:0015031 - protein transport
GO:0032511 - late endosome to vacuole transport via multivesicular body sorting pathway
GO:0036258 - multivesicular body assembly
and 3 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 307
Hs

1 219
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024