HitPredict

Interactor 1: ENY2 (Q9NPA8)
Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog)
Gene: ENY2

Interactor 2: UBP22 (Q9UPT9)
Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)
Gene: USP22

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 18206972, 35271311, 27601583, 24981860, 19615732
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EnY2~UCH, EnY2~zf-UBP
Common GO terms GO:0000124 - SAGA complex
GO:0003713 - transcription coactivator activity
GO:0005654 - nucleoplasm
GO:0006282 - regulation of DNA repair
GO:0006357 - regulation of transcription by RNA polymerase II
and 4 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 101
Hs

1 525
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024