Interactor 1: UBE2T (Q9NPD8)
Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T)
Gene: UBE2T
Interactor 2: FANCL (Q9NW38)
E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL)
Gene: FANCL
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.90 | 0.935 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25464845, 26046368, 33542213, 16916645, 24623813, 28162934, 30335751, 32092106, 31873223, 32420600, 33686268, 36385258, 21775430, 24389026, 19111657 |
| Identification Methods | protein complementation assay, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, molecular sieving, comigration in non denaturing gel electrophoresis |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FANCL_C~UQ_con |
| Common GO terms | GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0006513 - protein monoubiquitination and 2 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
