HitPredict

Interactor 1: CCL21 (O00585)
C-C motif chemokine 21 (6Ckine) (Beta-chemokine exodus-2) (Secondary lymphoid-tissue chemokine) (SLC) (Small-inducible cytokine A21)
Gene: CCL21

Interactor 2: CXL14 (O95715)
C-X-C motif chemokine 14 (Chemokine BRAK) (MIP-2G) (Small-inducible cytokine B14)
Gene: CXCL14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	28381538
Identification Methods	pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IL8~IL8
Common GO terms	GO:0005615 - extracellular space GO:0007267 - cell-cell signaling GO:0008009 - chemokine activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 134 Hs			1 111
+	Hs
		320109 CCL13_HUMAN (3-98): 6.52e-31: 107: 30.61		CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00
+	Hs
		320095 CCL11_HUMAN (16-99): 4.82e-27: 98.3: 33.33		CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00
+	Hs
		320105 CCL17_HUMAN (3-91): 4.76e-23: 87.9: 24.72		CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00
+	Hs
		320092 XCL1_HUMAN (1-97): 4.98e-22: 85.9: 21.65		CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00
+	Hs
		320085 CCL5_HUMAN (14-92): 1.97e-21: 83.6: 28.75		CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00
+	Hs
		320115 CCL26_HUMAN (26-95): 9.89e-19: 76.7: 28.57		CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00