HitPredict

Interactor 1: DCP1A (Q9NPI6)
mRNA-decapping enzyme 1A (EC 3.6.1.62) (Smad4-interacting transcriptional co-activator) (Transcription factor SMIF)
Gene: DCP1A

Interactor 2: DCP1A (Q9NPI6)
mRNA-decapping enzyme 1A (EC 3.6.1.62) (Smad4-interacting transcriptional co-activator) (Transcription factor SMIF)
Gene: DCP1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.841

The method score is based on:

Property Details
Experiments 16364915, 19966221
Identification Methods anti tag coimmunoprecipitation, fluorescence microscopy, x-ray crystallography, molecular sieving, static light scattering, nuclear magnetic resonance
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DCP1~DCP1, mRNA_decap_C~mRNA_decap_C
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005634 - nucleus
and 11 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 582
Hs

1 582
+ Hs
+ Dm
+ At
+ Hs
+ Sp
+ Hs
+ Mm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024