Interactor 1: MED4 (Q9NPJ6)
Mediator of RNA polymerase II transcription subunit 4 (Activator-recruited cofactor 36 kDa component) (ARC36) (Mediator complex subunit 4) (TRAP/SMCC/PC2 subunit p36 subunit) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36)
Gene: MED4

Interactor 2: MED9 (Q9NWA0)
Mediator of RNA polymerase II transcription subunit 9 (Mediator complex subunit 9)
Gene: MED9

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 14638676, 27684187, 15175163, 35271311, 25281560, 24981860, 33961781, 24882805
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med4~Med9
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 270
Hs

1 146
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024