Interactor 1: CCL21 (O00585)
C-C motif chemokine 21 (6Ckine) (Beta-chemokine exodus-2) (Secondary lymphoid-tissue chemokine) (SLC) (Small-inducible cytokine A21)
Gene: CCL21
Interactor 2: SDF1 (P48061)
Stromal cell-derived factor 1 (SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF) [Cleaved into: SDF-1-beta(3-72); SDF-1-alpha(3-67)]
Gene: CXCL12
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.51 | 1.00 | 0.716 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28381538 |
| Identification Methods | pull down, surface plasmon resonance, filter binding |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL8~IL8 |
| Common GO terms | GO:0005576 - extracellular region GO:0006955 - immune response GO:0007186 - G protein-coupled receptor signaling pathway GO:0008009 - chemokine activity GO:0042379 - chemokine receptor binding and 6 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
