HitPredict

Interactor 1: CCL21 (O00585)
C-C motif chemokine 21 (6Ckine) (Beta-chemokine exodus-2) (Secondary lymphoid-tissue chemokine) (SLC) (Small-inducible cytokine A21)
Gene: CCL21

Interactor 2: CXL17 (Q6UXB2)
C-X-C motif chemokine 17 (6-Cys CXCL17) (Dendritic cell and monocyte chemokine-like protein) (DMC) (VEGF coregulated chemokine 1) [Cleaved into: 4-Cys CXCL17]
Gene: CXCL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28381538
Identification Methods	pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 134 Hs			1 119
+	Hs
		1166407 CCL13_HUMAN (3-98): 6.52e-31: 107: 30.61		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		945620 CCL8_HUMAN (15-99): 3.13e-28: 101: 32.18		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		528221 CCL2_HUMAN (15-98): 1.51e-25: 94.4: 33.72		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166406 CCL17_HUMAN (3-91): 4.76e-23: 87.9: 24.72		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166409 XCL2_HUMAN (1-97): 1.27e-22: 87.5: 21.65		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		944668 CCL20_HUMAN (3-97): 6.39e-23: 87.5: 29.90		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		815515 XCL1_HUMAN (1-97): 4.98e-22: 85.9: 21.65		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		179467 CCL25_HUMAN (1-95): 3.32e-21: 84.8: 32.00		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		528267 CCL5_HUMAN (14-92): 1.97e-21: 83.6: 28.75		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166410 CCL26_HUMAN (26-95): 9.89e-19: 76.7: 28.57		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00