HitPredict

Interactor 1: JADE2 (Q9NQC1)
E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15)
Gene: JADE2

Interactor 2: ING3 (Q9NXR8)
Inhibitor of growth protein 3 (p47ING3)
Gene: ING3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 26496610, 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EPL1~ING
Common GO terms GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0043995 - histone H4K5 acetyltransferase activity
GO:0043996 - histone H4K8 acetyltransferase activity
GO:0043997 - histone H4K12 acetyltransferase activity
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 790
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024