HitPredict

Interactor 1: JADE2 (Q9NQC1)
E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15)
Gene: JADE2

Interactor 2: ING4 (Q9UNL4)
Inhibitor of growth protein 4 (p29ING4)
Gene: ING4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 26496610, 16387653, 26186194, 28514442, 30833792, 32296183, 24981860, 33961781, 20211142
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EPL1~ING
Common GO terms GO:0000123 - histone acetyltransferase complex
GO:0001558 - regulation of cell growth
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0046872 - metal ion binding
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 790
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024