Interactor 1: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 25923723, 29755980, 18636086
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0045087 - innate immune response
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 956
Hs

1 729
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024