HitPredict

Interactor 1: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Interactor 2: SF3B6 (Q9Y3B4)
Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa)
Gene: SF3B6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27591049
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 956 Hs			1 125
+	Hs
		441377 CYLD_HUMAN (1-956): 0: 1872: 100.00		RU2B_HUMAN (16-111): 5.15e-38: 129: 25.00
+	Hs
		1031473 CYLD_HUMAN (1-956): 0: 1872: 100.00		PABP4_HUMAN (12-99): 1.35e-22: 93.3: 22.47
+	Hs
		1119148 CYLD_HUMAN (1-956): 0: 1872: 100.00		PAP1L_HUMAN (3-111): 1.28e-22: 93.3: 21.82
+	Hs
		516708 CYLD_HUMAN (1-956): 0: 1872: 100.00		PABP1_HUMAN (20-99): 4.52e-21: 89.1: 23.46
+	Hs
		992953 CYLD_HUMAN (1-956): 0: 1872: 100.00		SRSF1_HUMAN (21-91): 3.36e-18: 79: 33.80