Interactor 1: INCE (Q9NQS7)
Inner centromere protein
Gene: INCENP

Interactor 2: AURKC (Q9UQB9)
Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)
Gene: AURKC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 32707033, 36736316, 15316025, 27332895
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type physical association, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains INCENP_ARK-bind~Pkinase
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005819 - spindle
GO:0030496 - midbody
GO:0032133 - chromosome passenger complex
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 918
Hs

1 309
+ Xl
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+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024