Interactor 1: EXOS5 (Q9NQT4)
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)
Gene: EXOSC5

Interactor 2: EXOS1 (Q9Y3B2)
Exosome complex component CSL4 (Exosome component 1)
Gene: EXOSC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 26496610, 30217970, 32296183, 11812149, 34133714, 12419256, 15231747, 25416956, 28514442, 27107012, 24981860, 33961781, 19060904, 31515488, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid, mammalian protein protein interaction trap, tandem affinity purification, barcode fusion genetics two hybrid and 2 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ECR1_N~RNase_PH, EXOSC1~RNase_PH, ECR1_N~RNase_PH_C
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 7 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 235
Hs

1 195
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Last updated: 15 Jul 2024