HitPredict

Interactor 1: ACKR2 (O00590)
Atypical chemokine receptor 2 (C-C chemokine receptor D6) (Chemokine receptor CCR-10) (Chemokine receptor CCR-9) (Chemokine-binding protein 2) (Chemokine-binding protein D6)
Gene: ACKR2

Interactor 2: CCL11 (P51671)
Eotaxin (C-C motif chemokine 11) (Eosinophil chemotactic protein) (Small-inducible cytokine A11)
Gene: CCL11

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9405404
Identification Methods	competition binding
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006954 - inflammatory response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 384 Hs			1 97
+	Hs
		849619 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL13_HUMAN (1-96): 8.14e-35: 116: 64.29
+	Hs
		561732 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CL3L1_HUMAN (1-92): 5.52e-34: 113: 39.36
+	Hs
		486237 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL3_HUMAN (1-92): 6.38e-33: 111: 38.71
+	Hs
		849504 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL11_HUMAN (1-97): 5.99e-33: 111: 100.00
+	Hs
		526564 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL4_HUMAN (1-91): 2.6e-32: 109: 39.79
+	Hs
		849614 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL7_HUMAN (17-96): 5.98e-31: 106: 67.07
+	Hs
		849616 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL14_HUMAN (1-91): 6.61e-31: 106: 32.98
+	Hs
		528210 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL2_HUMAN (1-96): 1.64e-30: 105: 70.41
+	Hs
		118813 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL24_HUMAN (1-97): 6.19e-29: 101: 35.05
+	Hs
		849613 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL18_HUMAN (1-92): 1.03e-27: 98.1: 34.78
+	Hs
		849617 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL15_HUMAN (1-89): 1.89e-25: 93.1: 29.09
+	Hs
		528252 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL5_HUMAN (1-90): 8.3e-25: 90.8: 42.86
+	Hs
		486231 CXCR5_HUMAN (25-354): 3.22e-88: 272: 31.11		CCL3_HUMAN (1-92): 6.38e-33: 111: 38.71
+	Hs
		849620 CCR3_HUMAN (20-360): 6.39e-99: 299: 36.71		CCL26_HUMAN (23-93): 1.16e-21: 82.7: 36.62
+	Hs
		526561 CXCR5_HUMAN (25-354): 3.22e-88: 272: 31.11		CCL4_HUMAN (1-91): 2.6e-32: 109: 39.79
+	Hs
		802290 XCR1_HUMAN (11-342): 2.52e-90: 276: 34.94		XCL1_HUMAN (1-95): 1.06e-23: 88.5: 29.47
+	Hs
		528245 CXCR5_HUMAN (25-354): 3.22e-88: 272: 31.11		CCL5_HUMAN (1-90): 8.3e-25: 90.8: 42.86
+	Mm
		500591 CCR3_MOUSE (33-360): 3.49e-79: 249: 35.44		CCL3_MOUSE (1-92): 1.14e-32: 110: 40.43
+	Hs
		180159 CXCR5_HUMAN (25-354): 3.22e-88: 272: 31.11		CCL16_HUMAN (1-87): 1.97e-21: 83.1: 30.44
+	Mm
		534669 CCR3_MOUSE (33-360): 3.49e-79: 249: 35.44		CCL4_MOUSE (1-91): 3.36e-27: 96.9: 36.56