HitPredict

Interactor 1: MYO5C (Q9NQX4)
Unconventional myosin-Vc
Gene: MYO5C

Interactor 2: CING (Q9P2M7)
Cingulin
Gene: CGN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Myosin_head~Myosin_tail_1
Common GO terms	GO:0016459 - myosin complex
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1742 Hs			1 1203
+	Hs
		725035 MYO5C_HUMAN (1-1742): 0: 1201: 100.00		MYH9_HUMAN (724-1202): 1.4e-22: 107: 15.91
+	Hs
		725086 MYO5A_HUMAN (1-1742): 0: 1090: 48.66		MYH9_HUMAN (724-1202): 1.4e-22: 107: 15.91
+	Hs
		725065 MYO5B_HUMAN (1-1742): 0: 1069: 47.12		MYH9_HUMAN (724-1202): 1.4e-22: 107: 15.91
+	Dm
		1303383 MYO7A_DROME (8-953): 0: 919: 34.11		MYSN_DROME (43-496): 4.47e-14: 79.8: 11.38
+	Hs
		502901 MYH3_HUMAN (748-1535): 6.19e-36: 152: 12.86		MYH6_HUMAN (31-998): 2.16e-36: 152: 10.54
+	Hs
		528356 MYH6_HUMAN (739-1351): 1.65e-29: 130: 11.97		MYH6_HUMAN (31-998): 2.16e-36: 152: 10.54
+	Hs
		502933 MYH3_HUMAN (748-1535): 6.19e-36: 152: 12.86		MYH4_HUMAN (615-1202): 7.6e-27: 121: 15.49
+	Hs
		528432 MYH13_HUMAN (741-1348): 1.23e-30: 134: 12.18		MYH8_HUMAN (615-1202): 1.36e-29: 130: 15.99
+	Hs
		528435 MYH4_HUMAN (741-1356): 1.52e-30: 134: 12.68		MYH8_HUMAN (615-1202): 1.36e-29: 130: 15.99
+	Rn
		361106 MYH6_RAT (1326-1735): 1.73e-12: 75.1: 9.02		MYH6_RAT (31-998): 9.92e-42: 169: 11.97
+	Hs
		522657 MYH4_HUMAN (741-1356): 1.52e-30: 134: 12.68		MYH7_HUMAN (85-700): 7.96e-23: 108: 13.02
+	Hs
		522585 MYH7_HUMAN (680-1363): 1.15e-29: 131: 10.31		MYH7_HUMAN (85-700): 7.96e-23: 108: 13.02
+	Dd
		445145 MYS2_DICDI (891-1351): 7.4e-10: 66.6: 22.53		MYS2_DICDI (523-1180): 2.79e-12: 73.9: 19.88