Interactor 1: BIRC6 (Q9NR09)
Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)
Gene: BIRC6
Interactor 2: DBLOH (Q9NR28)
Diablo IAP-binding mitochondrial protein (Diablo homolog, mitochondrial) (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) [Cleaved into: Diablo IAP-binding mitochondrial protein, cleaved form]
Gene: DIABLO
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.988 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 32877691, 33961781, 35941108, 15300255, 20957035, 15507451, 36758105, 36758106, 36758104, 15781261, 15200957, 22788920, 24302728 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, pull down, enzymatic study, x-ray crystallography, fluorescent resonance energy transfer, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BIR~Smac_DIABLO |
| Common GO terms | GO:0005829 - cytosol GO:0006915 - apoptotic process |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
