HitPredict

Interactor 1: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 16159877
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 783 Hs			1 2752
+	Hs
		1308896 DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		134254 DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		571636 DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		757803 IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		807854 DDX21_HUMAN (1-783): 0: 543: 100.00		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		1300955 DDX21_HUMAN (1-783): 0: 543: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		134074 DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		1300915 DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1271630 DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		134175 DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		571557 DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1344194 DDX21_HUMAN (1-783): 0: 543: 100.00		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		1154061 DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		133925 DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		134264 DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		757502 IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13