HitPredict

Interactor 1: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Interactor 2: MRCKB (Q9Y5S2)
Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)
Gene: CDC42BPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 783 Hs			1 1711
+	Hs
		149335 DDX21_HUMAN (1-783): 0: 543: 100.00		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		149013 DDX42_HUMAN (2-757): 4.87e-137: 430: 20.41		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		149221 DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		149137 DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		148373 DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		148153 DDX3Y_HUMAN (5-581): 7.35e-132: 408: 23.48		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		568751 DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		610756 DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		571309 DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		181744 DDX3Y_HUMAN (5-581): 7.35e-132: 408: 23.48		ST38L_HUMAN (1-421): 5.35e-120: 388: 37.93
+	Mm
		949303 DDX3X_MOUSE (5-575): 1.51e-136: 420: 23.55		TNIK_MOUSE (52-836): 1.02e-93: 335: 13.91
+	Hs
		571627 DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81		TNIK_HUMAN (52-833): 5.89e-94: 336: 14.30
+	Hs
		1073473 DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12		KS6A1_HUMAN (2-354): 1.8e-89: 310: 22.16
+	Hs
		149327 DDX4_HUMAN (205-551): 1.96e-53: 199: 37.60		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		148475 IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		757806 IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23		ST38L_HUMAN (1-421): 5.35e-120: 388: 37.93
+	Hs
		757621 IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23		STK38_HUMAN (4-421): 5.25e-119: 385: 38.77