Interactor 1: DPOE4 (Q9NR33)
DNA polymerase epsilon subunit 4 (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12)
Gene: POLE4

Interactor 2: DPOE3 (Q9NRF9)
DNA polymerase epsilon subunit 3 (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17)
Gene: POLE3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 32296183, 33961781, 10801849, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CBFD_NFYB_HMF~CBFD_NFYB_HMF
Common GO terms GO:0003887 - DNA-directed DNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006261 - DNA-templated DNA replication
GO:0008622 - epsilon DNA polymerase complex
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 117
Hs

1 147
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024