HitPredict

Interactor 1: ASH1L (Q9NR48)
Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.359) (EC 2.1.1.367) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H)
Gene: ASH1L

Interactor 2: MO4L1 (Q9UBU8)
Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (MRG15) (Protein MSL3-1) (Transcription factor-like protein MRG15)
Gene: MORF4L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	26186194, 28514442, 33961781, 30827843
Identification Methods	affinity chromatography technology, x-ray crystallography, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 2969 Hs			1 362
+	Hs
		1063048 ASH1L_HUMAN (1-2969): 0: 4109: 100.00		MO4L2_HUMAN (111-362): 3.81e-106: 314: 76.10
+	Dm
		1374944 ASH1_DROME (1729-2958): 0: 750: 31.76		EAF3_DROME (2-361): 1.73e-104: 315: 34.89
+	Hs
		1080440 EZH2_HUMAN (1928-2269): 4.34e-78: 278: 23.84		MO4L1_HUMAN (1-362): 3.85e-173: 487: 100.00
+	Hs
		1062986 EZH2_HUMAN (1928-2269): 4.34e-78: 278: 23.84		MO4L2_HUMAN (111-362): 3.81e-106: 314: 76.10