Interactor 1: TLR9 (Q9NR96)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21911421
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007249 - canonical NF-kappaB signal transduction
GO:0010008 - endosome membrane
and 6 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1032
Hs

1 522
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
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+ Hs
+ Hs

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Last updated: 15 Jul 2024