HitPredict

Interactor 1: TLR8 (Q9NR97)
Toll-like receptor 8 (CD antigen CD288)
Gene: TLR8

Interactor 2: TLR8 (Q9NR97)
Toll-like receptor 8 (CD antigen CD288)
Gene: TLR8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 23520111, 25599397, 23155421
Identification Methods molecular sieving, x-ray crystallography, x ray scattering, tox-r dimerization assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~LRR_8, TIR~TIR
Common GO terms GO:0000139 - Golgi membrane
GO:0001932 - regulation of protein phosphorylation
GO:0002224 - toll-like receptor signaling pathway
GO:0003677 - DNA binding
GO:0003723 - RNA binding
and 25 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1041
Hs

1 1041
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024