HitPredict

Interactor 1: PODXL (O00592)
Podocalyxin (GCTM-2 antigen) (Gp200) (Podocalyxin-like protein 1) (PC) (PCLP-1)
Gene: PODXL

Interactor 2: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030027 - lamellipodium GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 558 Hs			1 192
+	Hs
		134462 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		134457 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		134465 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Hs
		134458 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		134459 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		134434 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79
+	Hs
		297823 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		297812 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00
+	Hs
		892632 PDXL2_HUMAN (29-558): 3.21e-28: 120: 18.38		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		951406 PDXL2_HUMAN (29-558): 3.21e-28: 120: 18.38		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Ce
		136793 UNC89_CAEEL (6-463): 7.48e-23: 105: 10.85		RAC1_CAEEL (1-192): 6e-83: 245: 79.69
+	Hs
		925226 SOS1_HUMAN (14-314): 1.33e-20: 98.3: 9.46		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		297819 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		297827 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Hs
		297820 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Ce
		104464 UNC89_CAEEL (6-463): 7.48e-23: 105: 10.85		G5EBV3_CAEEL (2-192): 1.3e-77: 231: 62.30
+	Hs
		297809 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79
+	Ce
		136794 UNC89_CAEEL (6-463): 7.48e-23: 105: 10.85		CDC42_CAEEL (1-192): 1.77e-75: 226: 67.71