HitPredict

Interactor 1: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 2752
+	Hs
		807855 SIR7_HUMAN (1-400): 0: 535: 100.00		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		1127708 SIR7_HUMAN (1-400): 0: 535: 100.00		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		1302925 SIR7_HUMAN (1-400): 0: 535: 100.00		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		1154078 SIR7_HUMAN (1-400): 0: 535: 100.00		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		821054 SIR7_HUMAN (1-400): 0: 535: 100.00		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		1311999 SIR7_HUMAN (1-400): 0: 535: 100.00		DIDO1_HUMAN (13-1216): 9.01e-11: 70.1: 10.22
+	Hs
		1344557 SIR7_HUMAN (1-400): 0: 535: 100.00		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		1127669 SIR1_HUMAN (78-380): 5.06e-78: 257: 19.94		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Mm
		1265847 SIR1_MOUSE (78-380): 5.54e-78: 256: 19.94		NCOR2_MOUSE (1288-2719): 2e-19: 99: 10.73