HitPredict

Interactor 1: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Interactor 2: ICAM5 (Q9UMF0)
Intercellular adhesion molecule 5 (ICAM-5) (Telencephalin)
Gene: ICAM5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 22268729
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 924
+	Hs
		1356242 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		ICAM5_HUMAN (1-924): 1.33e-162: 501: 100.00
+	Hs
		400122 FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00		ICAM1_HUMAN (121-572): 8.18e-25: 111: 18.93
+	Hs
		1268542 FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00		PXDN_HUMAN (39-402): 5.53e-18: 91.8: 15.86
+	Hs
		1059133 FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00		ICAM4_HUMAN (33-235): 4.82e-16: 81.3: 34.14
+	Hs
		685320 FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00		L1CAM_HUMAN (505-783): 9.61e-12: 71.2: 27.62
+	Hs
		957565 FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00		PGBM_HUMAN (119-256): 2.86e-09: 63.5: 14.49
+	Hs
		1018314 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		CNTN1_HUMAN (12-778): 1.4e-52: 201: 11.81
+	Hs
		1356264 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		ROBO1_HUMAN (8-393): 4.28e-30: 131: 9.25
+	Hs
		1268546 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		PXDN_HUMAN (39-402): 5.53e-18: 91.8: 15.86
+	Hs
		685328 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		L1CAM_HUMAN (505-783): 9.61e-12: 71.2: 27.62
+	Hs
		957568 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		PGBM_HUMAN (119-256): 2.86e-09: 63.5: 14.49