HitPredict

Interactor 1: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Arfaptin~Arfaptin, PDZ~PDZ
Common GO terms GO:0001664 - G protein-coupled receptor binding
GO:0002092 - positive regulation of receptor internalization
GO:0005080 - protein kinase C binding
GO:0005102 - signaling receptor binding
GO:0005543 - phospholipid binding
and 35 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 415
Hs

1 415
+ Rn
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024