HitPredict

Interactor 1: STRN4 (Q9NRL3)
Striatin-4 (Zinedin)
Gene: STRN4

Interactor 2: STK24 (Q9Y6E0)
Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]
Gene: STK24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	17353931, 18782753, 35271311, 32707033, 23455922
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 753 Hs			1 443
+	Hs
		131609 STRN4_HUMAN (1-753): 0: 566: 100.00		STK25_HUMAN (24-434): 3.42e-136: 399: 72.26
+	Hs
		1344914 STRN4_HUMAN (1-753): 0: 566: 100.00		STK26_HUMAN (12-439): 6.21e-135: 395: 67.76
+	Hs
		1023123 STRN4_HUMAN (1-753): 0: 566: 100.00		STK4_HUMAN (27-315): 5.08e-129: 383: 52.22
+	Hs
		1027442 STRN4_HUMAN (1-753): 0: 566: 100.00		STK3_HUMAN (27-311): 8.23e-128: 380: 53.98
+	Hs
		1022891 STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27		STK24_HUMAN (1-443): 6.47e-163: 468: 100.00
+	Hs
		1217589 STRN4_HUMAN (1-753): 0: 566: 100.00		M4K3_HUMAN (29-404): 8.92e-117: 364: 38.86
+	Hs
		72974 STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27		B4DR80_HUMAN (23-443): 1.38e-139: 407: 94.77
+	Hs
		1022843 STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27		Q8NBY1_HUMAN (12-438): 1.22e-137: 401: 64.40
+	Hs
		131567 STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27		STK25_HUMAN (24-434): 3.42e-136: 399: 72.26
+	Hs
		1022877 STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27		STK26_HUMAN (12-439): 6.21e-135: 395: 67.76
+	Rn
		936839 STRN_RAT (36-753): 6.92e-148: 453: 48.17		AKT3_RAT (3-361): 5.65e-134: 395: 24.52
+	Hs
		1022811 STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27		STK4_HUMAN (27-315): 5.08e-129: 383: 52.22
+	Hs
		1022814 STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27		STK3_HUMAN (27-311): 8.23e-128: 380: 53.98
+	Hs
		1018195 STRN4_HUMAN (1-753): 0: 566: 100.00		M4K2_HUMAN (31-324): 6.41e-78: 259: 45.55
+	Hs
		1344920 STRN4_HUMAN (1-753): 0: 566: 100.00		TNIK_HUMAN (31-316): 7.58e-72: 248: 44.70
+	Hs
		1272899 STRN4_HUMAN (1-753): 0: 566: 100.00		M4K1_HUMAN (31-286): 4.72e-71: 241: 45.08
+	Mm
		885679 STRN4_MOUSE (1-753): 3.92e-177: 527: 94.21		TNIK_MOUSE (31-316): 6.3e-72: 248: 44.70
+	Mm
		949415 STRN3_MOUSE (29-753): 1.18e-158: 481: 49.01		TNIK_MOUSE (31-316): 6.3e-72: 248: 44.70
+	Hs
		1022881 STRN3_HUMAN (22-753): 8.07e-152: 463: 48.27		TNIK_HUMAN (31-316): 7.58e-72: 248: 44.70
+	Mm
		223076 STRN_MOUSE (36-753): 1.45e-147: 452: 48.05		TNIK_MOUSE (31-316): 6.3e-72: 248: 44.70