HitPredict

Interactor 1: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.893

The method score is based on:

Property Details
Experiments 26578655, 25670202, 28205554, 24255178
Identification Methods fluorescent resonance energy transfer, pull down, enzymatic study, proximity labelling technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000922 - spindle pole
GO:0001827 - inner cell mass cell fate commitment
GO:0001828 - inner cell mass cellular morphogenesis
GO:0004674 - protein serine/threonine kinase activity
and 20 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1088
Hs

1 1088
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024