HitPredict

Interactor 1: UBQL4 (Q9NRR5)
Ubiquilin-4 (Ataxin-1 interacting ubiquitin-like protein) (A1Up) (Ataxin-1 ubiquitin-like-interacting protein A1U) (Connexin43-interacting protein of 75 kDa) (CIP75)
Gene: UBQLN4

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 30442662, 34349018, 16713569
Identification Methods affinity chromatography technology, cross-linking study, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains UBA~UBA, UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 3 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 601
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024