HitPredict

Interactor 1: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Interactor 2: S12A6 (Q9UHW9)
Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)
Gene: SLC12A6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Hs			1 1150
+	Hs
		592560 RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78		S12A6_HUMAN (1-1150): 0: 1261: 100.00
+	Hs
		844784 RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98		S12A6_HUMAN (1-1150): 0: 1261: 100.00
+	Mm
		722747 RAB6A_MOUSE (1-208): 9.38e-85: 251: 90.87		S12A6_MOUSE (1-1150): 0: 1262: 98.17
+	Mm
		722722 RAB5C_MOUSE (3-207): 2.45e-89: 263: 40.98		S12A4_MOUSE (100-1150): 0: 1112: 77.78
+	Mm
		722750 RAB6A_MOUSE (1-208): 9.38e-85: 251: 90.87		S12A4_MOUSE (100-1150): 0: 1112: 77.78
+	Hs
		592582 RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		844800 RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		1345123 RAB6B_HUMAN (1-208): 4.46e-87: 257: 100.00		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Mm
		1265035 RAB1B_MOUSE (7-206): 2.65e-87: 257: 36.50		S12A5_MOUSE (76-1150): 0: 1090: 68.03
+	Hs
		592616 RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		844814 RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		592178 RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		844455 RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		873901 RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		592173 RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		844449 RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		854872 RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		676522 RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98		CTR1_HUMAN (231-668): 3.36e-86: 294: 13.90
+	Hs
		592206 RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78		LAT1_HUMAN (231-752): 6.68e-80: 273: 12.08
+	Hs
		844488 RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98		LAT1_HUMAN (231-752): 6.68e-80: 273: 12.08