HitPredict

Interactor 1: TOPRS (Q9NS56)
E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3)
Gene: TOPORS

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35944360
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1045 Hs			1 708
+	Hs
		1154082 NIPBL_HUMAN (362-1016): 7.16e-73: 267: 13.73		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1246383 THOC2_HUMAN (485-913): 3.17e-29: 128: 12.14		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1261766 DC2I1_HUMAN (552-1024): 8.69e-22: 104: 9.85		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1148068 S31H1_HUMAN (490-854): 1.8e-13: 77.4: 16.85		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1304767 SCAFB_HUMAN (465-951): 2.34e-12: 73.5: 13.03		ZRAN1_HUMAN (1-697): 0: 987: 100.00