HitPredict

Interactor 1: KCIP2 (Q9NS61)
Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Cardiac voltage-gated potassium channel modulatory subunit) (Potassium channel-interacting protein 2)
Gene: KCNIP2

Interactor 2: KCIP1 (Q9NZI2)
Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein)
Gene: KCNIP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 15358149
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~EF-hand_7, EF-hand_7~EF-hand_8, EF-hand_8~EF-hand_8
Common GO terms GO:0005267 - potassium channel activity
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0008076 - voltage-gated potassium channel complex
and 4 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 270
Hs

1 227
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Last updated: 15 Jul 2024