HitPredict

Interactor 1: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18

Interactor 2: POLH (Q9Y253)
DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein)
Gene: POLH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.743

The method score is based on:

Property Details
Experiments 29590477, 16824193, 18363965, 21098111, 15359278, 21396873, 23345618
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005657 - replication fork
GO:0006281 - DNA repair
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 495
Hs

1 713
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024