Interactor 1: SYFB (Q9NSD9)
Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)
Gene: FARSB
Interactor 2: SYFA (Q9Y285)
Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (CML33) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS)
Gene: FARSA
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.968 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 33961781, 37071682, 26186194, 28514442, 20223217, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, cross-linking study, molecular sieving, x-ray crystallography, pull down, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | B3_4~tRNA-synt_2d, B5~tRNA-synt_2d, PhetRS_B1~tRNA-synt_2d, PheRS_DBD1~tRNA_synthFbeta, tRNA-synt_2d~tRNA_synthFbeta |
| Common GO terms | GO:0000287 - magnesium ion binding GO:0003723 - RNA binding GO:0004826 - phenylalanine-tRNA ligase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm and 5 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
