Interactor 1: SIR3 (Q9NTG7)
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)
Gene: SIRT3
Interactor 2: SIR5 (Q9NXA8)
NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 2.3.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5)
Gene: SIRT5
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17715127 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SIR2~SIR2 |
| Common GO terms | GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0006476 - protein deacetylation GO:0008270 - zinc ion binding and 5 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Ec | |
|
|||||||||||
| + | Hp |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
