HitPredict

Interactor 1: MDN1 (Q9NU22)
Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein)
Gene: MDN1

Interactor 2: NLE1 (Q9NVX2)
Notchless protein homolog 1
Gene: NLE1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26601951, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 5596 Hs			1 485
+	Mm
		925844 DYHC1_MOUSE (802-2223): 2.26e-143: 510: 13.77		LIS1_MOUSE (2-275): 3.14e-74: 241: 21.36
+	Hs
		792984 DYHC1_HUMAN (802-2223): 6.07e-143: 508: 13.58		LIS1_HUMAN (2-275): 4.65e-74: 241: 21.36
+	Hs
		1051633 DYHC1_HUMAN (802-2223): 6.07e-143: 508: 13.58		FBXW7_HUMAN (6-352): 2.75e-69: 236: 21.41
+	Hs
		903222 DYHC1_HUMAN (802-2223): 6.07e-143: 508: 13.58		WDR5_HUMAN (2-231): 8.42e-54: 185: 19.92
+	Dm
		741114 DYHC_DROME (1052-2223): 4.41e-139: 495: 13.29		LIS1_DROME (365-484): 3.38e-31: 126: 35.54
+	Sc
		630897 MDN1_YEAST (1698-2416): 2.89e-50: 202: 18.90		NLE1_YEAST (2-314): 3.8e-78: 254: 19.61
+	Hs
		725215 MYH10_HUMAN (4403-5388): 1.78e-29: 133: 10.48		FBXW7_HUMAN (6-352): 2.75e-69: 236: 21.41
+	Hs
		724952 MYH9_HUMAN (4810-5327): 5.69e-14: 81.9: 9.46		FBXW7_HUMAN (6-352): 2.75e-69: 236: 21.41
+	Ce
		1090472 DYHC_CAEEL (5248-5561): 1.54e-10: 70.7: 10.94		LIS1_CAEEL (2-275): 2.08e-61: 207: 19.93
+	Hs
		903375 BD1L1_HUMAN (4818-5348): 1.21e-16: 90.7: 11.11		WDR5_HUMAN (2-231): 8.42e-54: 185: 19.92
+	Sp
		252177 MDN1_SCHPO (2219-2383): 5.52e-10: 68.8: 25.00		NLE1_SCHPO (2-142): 1.26e-31: 128: 16.31
+	Hs
		728492 MYH11_HUMAN (4414-5112): 2.34e-16: 90: 10.92		POC1A_HUMAN (4-85): 3.63e-17: 85.1: 13.42