HitPredict

Interactor 1: STAU2 (Q9NUL3)
Double-stranded RNA-binding protein Staufen homolog 2
Gene: STAU2

Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24778252
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~dsrm, Ribonuclease_3~dsrm
Common GO terms	GO:0003723 - RNA binding GO:0003725 - double-stranded RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 570 Hs			1 1922
+	Hs
		269939 PRKRA_HUMAN (2-273): 4.61e-41: 152: 18.69		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Mm
		956560 TRBP2_MOUSE (2-194): 3.59e-35: 137: 20.83		DICER_MOUSE (1-1922): 0: 1774: 92.88
+	Hs
		323319 STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		1286219 STAU2_HUMAN (1-570): 0: 555: 100.00		DHX58_HUMAN (43-638): 2.57e-80: 282: 21.70
+	At
		1108230 DCL1_ARATH (73-375): 2.9e-42: 165: 19.75		DCL2_ARATH (1424-1913): 3.21e-96: 345: 24.47
+	At
		1340357 DRB2_ARATH (208-392): 1.2e-32: 131: 21.16		DCL3_ARATH (892-1913): 8.76e-90: 326: 16.96
+	Hs
		269869 PRKRA_HUMAN (2-273): 4.61e-41: 152: 18.69		IFIH1_HUMAN (33-641): 7.5e-85: 304: 19.44
+	Hs
		269593 PRKRA_HUMAN (2-273): 4.61e-41: 152: 18.69		RIGI_HUMAN (34-641): 5.74e-79: 284: 19.97
+	Hs
		322980 STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33		DHX58_HUMAN (43-638): 2.57e-80: 282: 21.70
+	Hs
		322157 STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33		DDX5_HUMAN (6-364): 3.03e-66: 239: 11.54
+	Hs
		269805 PRKRA_HUMAN (2-273): 4.61e-41: 152: 18.69		DDX55_HUMAN (14-339): 3.13e-47: 182: 8.67
+	Hs
		322273 STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33		IF4A3_HUMAN (6-251): 1.27e-52: 193: 11.37
+	Hs
		322901 STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33		DDX55_HUMAN (14-339): 3.13e-47: 182: 8.67
+	Dm
		55497 Q9VLW8_DROME (109-333): 8.08e-39: 146: 19.82		DCR2_DROME (763-1448): 4.62e-34: 146: 10.54
+	Dm
		1181378 Q9V9V7_DROME (65-456): 1.52e-58: 208: 14.32		Q7KNF1_DROME (1664-1862): 5.55e-12: 73.5: 19.53
+	At
		1352640 DCL1_ARATH (73-375): 2.9e-42: 165: 19.75		DCL1_ARATH (1668-1850): 6.62e-19: 96.6: 19.51
+	Hs
		322873 STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33		ASCC3_HUMAN (13-493): 5.92e-31: 136: 11.18
+	Hs
		271998 STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33		U520_HUMAN (4-505): 1.16e-29: 132: 10.93
+	At
		1352485 DRB2_ARATH (208-392): 1.2e-32: 131: 21.16		DCL1_ARATH (1668-1850): 6.62e-19: 96.6: 19.51
+	Dm
		1363205 LOQS_DROME (7-379): 6.2e-34: 136: 16.20		DCR1_DROME (1582-1767): 1.61e-11: 72.3: 20.41