HitPredict

Interactor 1: MED17 (Q9NVC6)
Mediator of RNA polymerase II transcription subunit 17 (Activator-recruited cofactor 77 kDa component) (ARC77) (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80)
Gene: MED17

Interactor 2: MED23 (Q9ULK4)
Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)
Gene: MED23

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 0.60 0.671

The method score is based on:

Property Details
Experiments 25281560, 33961781, 35271311
Identification Methods proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
GO:0006357 - regulation of transcription by RNA polymerase II
and 6 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 651
Hs

1 1368
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024