Interactor 1: RPC2 (Q9NW08)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)
Gene: POLR3B

Interactor 2: RPC8 (Q9Y535)
DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit H) (RNA polymerase III subunit 22.9 kDa subunit) (RPC22.9)
Gene: POLR3H

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 33961781, 35271311, 17643375, 24981860, 33674783
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rbc25~RNA_pol_Rpb2_7, RNA_pol_Rpb2_7~SHS2_Rpb7-N
Common GO terms GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1133
Hs

1 204
+ Hs
+ Dm
+ Hs
+ Sc
+ Hs
+ Hs
+ Sp
+ Sc
+ Pf
+ Hs
+ Hs

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Last updated: 15 Jul 2024