HitPredict

Interactor 1: RBM28 (Q9NW13)
RNA-binding protein 28 (RNA-binding motif protein 28)
Gene: RBM28

Interactor 2: SRPK3 (Q9UPE1)
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)
Gene: SRPK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	33961781, 32707033
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 567
+	Hs
		942981 RBM28_HUMAN (1-759): 7.97e-129: 402: 100.00		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		836027 RBM28_HUMAN (1-759): 7.97e-129: 402: 100.00		GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87
+	Hs
		1302070 RBM28_HUMAN (1-759): 7.97e-129: 402: 100.00		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Sp
		143387 RSD1_SCHPO (5-230): 7.18e-11: 67.4: 26.16		DSK1_SCHPO (3-565): 8.43e-109: 338: 35.27
+	Hs
		516362 PABP1_HUMAN (325-757): 1.9e-34: 141: 12.63		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Hs
		516460 PABP1_HUMAN (325-757): 1.9e-34: 141: 12.63		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		942631 PABP4_HUMAN (329-750): 1.23e-33: 139: 13.39		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		516419 PABP1_HUMAN (325-757): 1.9e-34: 141: 12.63		GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87
+	Hs
		516416 PABP1_HUMAN (325-757): 1.9e-34: 141: 12.63		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		516651 PABP1_HUMAN (325-757): 1.9e-34: 141: 12.63		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Hs
		833945 PABP5_HUMAN (318-666): 1.89e-26: 114: 13.21		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		943042 RBM19_HUMAN (5-113): 3.64e-10: 65.5: 21.10		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Rn
		78186 B5DF80_RAT (325-757): 6.37e-35: 143: 12.61		MK03_RAT (75-267): 1.43e-44: 164: 20.90
+	Rn
		600488 PABP1_RAT (325-757): 1.19e-34: 142: 12.63		MK03_RAT (75-267): 1.43e-44: 164: 20.90
+	Rn
		102586 G3V9N0_RAT (329-750): 1.03e-33: 139: 14.10		MK03_RAT (75-267): 1.43e-44: 164: 20.90
+	Sc
		648352 NSR1_YEAST (5-189): 3.65e-13: 73.9: 31.38		HOG1_YEAST (75-372): 3.16e-47: 172: 16.94
+	Hs
		516417 PABP1_HUMAN (325-757): 1.9e-34: 141: 12.63		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		834033 PABP4_HUMAN (329-750): 1.23e-33: 139: 13.39		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		834096 PABP5_HUMAN (318-666): 1.89e-26: 114: 13.21		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Sp
		143391 RSD1_SCHPO (5-230): 7.18e-11: 67.4: 26.16		LKH1_SCHPO (404-565): 1.99e-12: 72: 27.81