Interactor 1: FANCL (Q9NW38)
E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL)
Gene: FANCL

Interactor 2: FANCL (Q9NW38)
E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL)
Gene: FANCL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 16916645, 17396147
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FANCL_C~FANCL_C, FANCL_C~FANCL_d1, FANCL_C~FANCL_d2, FANCL_C~FANCL_d3, FANCL_d2~FANCL_d2, FANCL_d2~FANCL_d3
Common GO terms GO:0000785 - chromatin
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005654 - nucleoplasm
and 13 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 375
Hs

1 375
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024