HitPredict

Interactor 1: NALP2 (Q9NX02)
NACHT, LRR and PYD domains-containing protein 2 (Nucleotide-binding site protein 1) (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2)
Gene: NLRP2

Interactor 2: FAF1 (Q9UNN5)
FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A)
Gene: FAF1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	17046979
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006915 - apoptotic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1062 Hs			1 650
+	Hs
		886433 NAL12_HUMAN (9-1041): 0: 731: 31.69		FAF1_HUMAN (1-650): 0: 840: 100.00
+	Hs
		1202840 NAL10_HUMAN (1-673): 2.9e-145: 451: 23.20		FAF1_HUMAN (1-650): 0: 840: 100.00
+	Hs
		1299046 NLRP3_HUMAN (847-1058): 2.4e-36: 151: 33.49		FAF1_HUMAN (1-650): 0: 840: 100.00
+	Hs
		1263228 NALP7_HUMAN (800-1058): 3e-15: 82.8: 21.64		FAF1_HUMAN (1-650): 0: 840: 100.00
+	Hs
		1318403 NALP2_HUMAN (1-1062): 0: 785: 100.00		UBXN6_HUMAN (395-645): 7.43e-34: 136: 15.73
+	Hs
		1200101 NLRX1_HUMAN (839-1034): 4.6e-12: 72.4: 22.73		FAF1_HUMAN (1-650): 0: 840: 100.00