HitPredict

Interactor 1: MCM9 (Q9NXL9)
DNA helicase MCM9 (hMCM9) (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9)
Gene: MCM9

Interactor 2: MCM8 (Q9UJA3)
DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8)
Gene: MCM8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 26186194, 28514442, 26870752, 26215093, 26300262, 23401855, 33961781, 32528060
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0003682 - chromatin binding
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 15 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1143
Hs

1 840
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Last updated: 15 Jul 2024