HitPredict

Interactor 1: NDE1 (Q9NXR1)
Nuclear distribution protein nudE homolog 1 (NudE)
Gene: NDE1

Interactor 2: AP4E1 (Q9UPM8)
AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin)
Gene: AP4E1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 335 Hs			1 1137
+	Hs
		1326034 NDEL1_HUMAN (3-316): 1.44e-65: 212: 56.78		AP4E1_HUMAN (1-1137): 0: 1063: 100.00
+	Hs
		302112 EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44		AP2A2_HUMAN (25-941): 0: 637: 18.26
+	Hs
		787890 EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44		AP2B1_HUMAN (59-902): 0: 636: 14.14
+	Hs
		212604 EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44		AP1G1_HUMAN (30-847): 0: 631: 20.96
+	Rn
		923853 Q5JC29_RAT (4-255): 3.17e-36: 140: 13.76		AP2B1_RAT (59-902): 0: 636: 14.14
+	Rn
		1126749 Q5JC29_RAT (4-255): 3.17e-36: 140: 13.76		Q66HM2_RAT (25-941): 0: 635: 18.52
+	Mm
		567515 EPS15_MOUSE (4-255): 4.39e-34: 134: 11.90		AP2A2_MOUSE (25-941): 0: 641: 18.33
+	Hs
		321504 EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44		AP2A1_HUMAN (25-913): 0: 623: 18.70
+	Rn
		88764 Q5JC29_RAT (4-255): 3.17e-36: 140: 13.76		D3ZUY8_RAT (25-913): 0: 631: 19.36
+	Mm
		788007 EPS15_MOUSE (4-255): 4.39e-34: 134: 11.90		AP2B1_MOUSE (59-902): 0: 635: 14.14
+	Hs
		724758 MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18		AP2B1_HUMAN (59-902): 0: 636: 14.14
+	Hs
		321498 MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18		AP2A1_HUMAN (25-913): 0: 623: 18.70
+	Hs
		787903 EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44		AP1B1_HUMAN (59-901): 0: 598: 13.84