HitPredict

Interactor 1: TBA8 (Q9NY65)
Tubulin alpha-8 chain (EC 3.6.5.-) (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Cleaved into: Dephenylalaninated tubulin alpha-8 chain]
Gene: TUBA8

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23703321
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 1215
+	Hs
		1309525 TBA1C_HUMAN (1-449): 0: 717: 89.76		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		933651 TBA4A_HUMAN (1-448): 0: 710: 89.96		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		933376 TBA1B_HUMAN (1-439): 0: 706: 90.89		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1175219 TBA1A_HUMAN (1-439): 0: 704: 90.89		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		428477 TBB5_HUMAN (1-439): 0: 694: 39.41		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		934008 TBB4B_HUMAN (1-437): 0: 691: 39.13		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Mm
		933747 TBA1A_MOUSE (1-439): 0: 704: 90.89		HDAC6_MOUSE (1-1215): 0: 1345: 74.32
+	Hs
		428188 TBB5_HUMAN (1-439): 0: 694: 39.41		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		933791 TBB4B_HUMAN (1-437): 0: 691: 39.13		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		880679 TBA4A_HUMAN (1-448): 0: 710: 89.96		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Hs
		1175252 TBA1A_HUMAN (1-439): 0: 704: 90.89		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Hs
		428112 TBB5_HUMAN (1-439): 0: 694: 39.41		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Hs
		428502 TBB5_HUMAN (1-439): 0: 694: 39.41		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Hs
		934028 TBB4B_HUMAN (1-437): 0: 691: 39.13		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48