HitPredict

Interactor 1: IMA3 (O00629)
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Gene: KPNA4

Interactor 2: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.929

Property	Details
Experiments	26186194, 28514442, 33961781, 17855385, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Arm~RCC1, Arm_3~RCC1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 421
+	Hs
		131376 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Sc
		601771 IMA1_YEAST (2-521): 1.2e-140: 417: 44.90		RCC1_YEAST (192-419): 1.22e-30: 124: 18.85