HitPredict

Interactor 1: APC11 (Q9NYG5)
Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein)
Gene: ANAPC11

Interactor 2: APC4 (Q9UJX5)
Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)
Gene: ANAPC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.746

The method score is based on:

Property	Details
Experiments	35271311, 12956947, 26083744, 25490258, 29549242, 21926987, 23078409, 25043029
Identification Methods	affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005680 - anaphase-promoting complex GO:0005829 - cytosol GO:0007346 - regulation of mitotic cell cycle and 4 others more... GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0051301 - cell division GO:0051445 - regulation of meiotic cell cycle GO:0070979 - protein K11-linked ubiquitination
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	84
Hs

1	808

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024