Interactor 1: APC11 (Q9NYG5)
Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein)
Gene: ANAPC11

Interactor 2: ANC2 (Q9UJX6)
Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)
Gene: ANAPC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.916

The method score is based on:

Property Details
Experiments 12956947, 11739784, 35271311, 10230407, 24163370
Identification Methods affinity chromatography technology, pull down, two hybrid, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC2~zf-ANAPC11, Cullin~zf-ANAPC11
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 84
Hs

1 822
+ At
+ Dm
+ Mm
+ Hs
+ At
+ Hs
+ Mm
+ At
+ Sc
+ Dm
+ Hs
+ Mm
+ Hs
+ Dm
+ At
+ Hs
+ Dm
+ Sp
+ Dm
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024