HitPredict

Interactor 1: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35944360
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070530 - K63-linked polyubiquitin modification-dependent protein binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 693 Hs			1 708
+	Hs
		1234345 TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1186098 MICA3_HUMAN (139-605): 2.54e-25: 114: 11.18		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		980015 IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1350242 CHD7_HUMAN (18-590): 1.32e-19: 96.3: 11.81		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		257716 ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		203257 SYNJ1_HUMAN (303-658): 3.22e-09: 62.5: 9.55		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		847107 SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1290081 TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Mm
		1208623 MICA3_MOUSE (136-604): 1.25e-34: 144: 11.13		OTU7A_MOUSE (299-701): 3.22e-123: 391: 25.33
+	Hs
		1234333 TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73